Human well-being and capabilities are at the core of the transformations envisaged by the 2030 Agenda. This short policy brief reviews how investments in social protection, education and health care can help reduce poverty and inequality, boost well-being and enhance capabilities for all in Asia and the Pacific. The brief is a shortened version of the profile for Entry Point 1: Human Wellbeing and Capabilities, prepared as a background note for the Asian and Pacific Forum for Sustainable Development 2020.