Asia-Pacific is the most disaster-prone region of the world. In recent years, it has faced a series of multiple exogenous shocks that transcend geographical boundaries and endanger our communities. The poor and the vulnerable are the ones most affected. Despite the rapid economic growth in the region, many developing countries are increasingly vulnerable to disasters, and the magnitude and frequency of extreme disasters are estimated to rise due to the effects of climate change. This necessitates building resilience of the region to extreme disasters in multidimensional ways. Over the past few decades, Space technology and Geographic Information Systems (GIS) applications have become indispensable part of the modern information society. As disasters become more and more frequent and intense, the demand for these technologies is increasing in order to save lives, to minimize economic losses and to build resilience of the Asia-Pacific region. It is imperative that the policymakers and decision makers make concerted efforts to widen and deepen the use of space technology and GIS applications in the Asia-Pacific region to mitigate the effect of disasters.